Drug details

Thiola (topronin delayed-release tablets)

type of Nephrolithiasis

Thiola (tiopronin) is an active reducing agent indicated for the prevention of cystine (kidney) stone formation in patients with severe homozygous cystinuria with urinary cystine greater than 500 mg/day, who are resistant to treatment with conservative measures of high fluid intake, alkali and diet modification, or who have adverse reactions to d-penicillamine.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • rash,
  • fever,
  • swollen glands,
  • joint pain,
  • puffy eyes,
  • swelling in your ankles or feet,
  • weight gain, and
  • foamy urine
The following drugs are related to Thiola, either as a replacement or used together:
  • Uroxatral (alfuzosin hcl)
  • Zyloprim (allopurinol)
  • Cuprimine (penicillamine)
  • Flomax (tamsulosin hydrochloride)
  • Procardia (nifedipine)
  • Procardia XL (nifedipine extended release tablets)
  • Thiola (topronin delayed-release tablets)