Drug details

Vosevi (sofosbuvir)

type of Hepatitis B Hepatitis C Agents, HCV Polymerase Inhibitors

Vosevi (sofosbuvir, velpatasvir, and voxilaprevir) tablets are a fixed-dose combination of a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor, an HCV NS5A inhibitor, and an HCV NS3/4A protease inhibitor, indicated for the treatment of adult patients with chronic HCV infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have genotype 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing an NS5A inhibitor; or genotype 1a or 3 infection and have previously been treated with an HCV regimen containing sofosbuvir without an NS5A inhibitor.

The drug is often used to treat Cirrhosis , Hepatitis C .

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • loss of appetite,
  • dark urine,
  • vomiting,
  • diarrhea,
  • easy bruising,
  • unusual bleeding,
  • lightheadedness,
  • shortness of breath,
  • confusion,
  • tiredness,
  • chest pain,
  • weakness, and
  • right-sided upper stomach pain,
  • memory problems,
  • yellowing of your skin or eyes (jaundice),
  • very slow heartbeats,
  • black or bloody stools,
  • vomiting blood,
  • extreme tiredness
The following drugs are related to Vosevi, either as a replacement or used together:
  • Moderiba (ribavirin tablets)