Drug details

Roctavian (valoctocogene roxaparvovec-rvox suspension)

type of Clotting Factors, Gene Therapy

Roctavian (valoctocogene roxaparvovec-rvox) is an adeno-associated virus vector-based gene therapy indicated for the treatment of adults with severe hemophilia A (congenital factor VIII deficiency with factor VIII activity less than 1 IU/dL) without pre-existing antibodies to adeno-associated virus serotype 5 detected by an FDA-approved test.

This drug may have the following side effects:
  • nausea,
  • rash,
  • vomiting,
  • diarrhea,
  • headache,
  • fatigue,
  • abdominal pain,
  • dizziness, and
The following drugs are related to Roctavian, either as a replacement or used together:
  • Advate ([antihemophilic factor (recombinant), plasma/albumin-free method] for intravenous injection)
  • Adynovate (antihemophilic factor (recombinant), pegylated for injection)
  • Afstyla (antihemophilic factor recombinant intravenous injection)
  • Alphanate (antihemophilic factor)
  • Amicar (aminocaproic acid)
  • Feiba VH (anti-inhibitor coagulant complex, vapor heated)
  • Xyntha (antihemophilic factor)
  • Kogenate FS (antihemophilic factor (recombinant))
  • Novoeight (antihemophilic factor (recombinant) lyophilized powder for intravenous injection)
  • Eloctate (antihemophilic factor (recombinant), fc fusion protein for intravenous infusion)
  • Jivi (antihemophilic factor (recombinant), pegylated-aucl for injection)
  • Nuwiq (antihemophilic factor recombinant intravenous infusion)
  • Cyklokapron (tranexamic acid)
  • DDAVP (desmopressin acetate tablets)
  • DDAVP Injection (desmopressin acetate injection)
  • DDAVP Nasal Spray (desmopressin acetate nasal spray)
  • DDAVP Rhinal Tube (desmopressin acetate rhinal tube)
  • Stimate (desmopressin acetate nasal spray)
  • Hemlibra (emicizumab-kxwh injection, for subcutaneous use)
  • Esperoct ([antihemophilic factor (recombinant), glycopegylated-exei] injection)
  • Hemofil-M ([antihemophilic factor (human), method m, monoclonal purified] nanofiltered)