Drug details

Zynyz (retifanlimab-dlwr)

type of PD-1PD-L1 Inhibitors

Zynyz (retifanlimab-dlwr) is a programmed death receptor-1 (PD-1)–blocking antibody indicated for the treatment of adult patients with metastatic or recurrent locally advanced Merkel cell carcinoma.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • loss of appetite,
  • itching,
  • dark urine,
  • rash,
  • diarrhea,
  • fever,
  • easy bruising,
  • unusual bleeding,
  • shortness of breath,
  • tiredness,
  • stomach pain,
  • chest pain,
  • dizziness,
  • constipation,
  • fainting,
  • cough,
  • increased thirst,
  • headaches,
  • mood changes,
  • irritability,
  • hair loss,
  • feeling cold,
  • hunger,
  • severe nausea,
  • yellowing of your skin or eyes (jaundice),
  • frequent urination,
  • increased sweating,
  • red or pink urine,
  • little or no urine,
  • severe vomiting,
  • decreased sex drive,
  • black or tarry stools,
  • swollen lymph nodes
  • forgetfulness,
  • weight gain or loss,
  • flu-like symptoms, and
  • swelling of your feet or ankles,
  • skin that blisters or peels,
  • pain on the right side of your abdomen,
  • increase sensitivity to light,
  • rapid heart beat,
  • deepened voice,
  • sores in your mouth or nose, throat, or genital area,
The following drugs are related to Zynyz, either as a replacement or used together:
  • Fotivda (tivozanib capsules)
  • Keytruda (pembrolizumab for injection)