Drug details
Retevmo (selpercatinib capsules)
type of Antineoplastics, VEGF Inhibitor, RET Kinase Inhibitors
Retevmo (selpercatinib) is a kinase inhibitor used to treat adult patients with metastatic RET fusion-positive non-small cell lung cancer (NSCLC), adult and pediatric patients 12 years of age and older with advanced or metastatic RET-mutant medullary thyroid cancer (MTC) who require systemic therapy, and adult and pediatric patients 12 years of age and older with advanced or metastatic RET fusion-positive thyroid cancer who require systemic therapy and who are radioactive iodine-refractory (if radioactive iodine is appropriate).
This drug may have the following side effects:
- rash,
- diarrhea,
- dry mouth,
- fatigue,
- constipation
- decreased platelets,
- increased creatinine,
- high blood pressure (hypertension),
- fluid retention (edema),
- increased alkaline phosphatase,
- decreased leukocytes,
- decreased calcium,
- decreased albumin,
- decreased sodium, and
- increased aspartate aminotransferase (AST),
- increased alanine aminotransferase (ALT),
- increased blood sugar (glucose),
- increased total cholesterol,
The following drugs are related to Retevmo, either as a replacement or used together:
- Alimta (pemetrexed)
- Alymsys (bevacizumab-maly injection)
- Tecentriq (atezolizumab injection)
- Avastin (bevacizumab)
- Zirabev (bevacizumab-bvzr injection)
- Tabrecta (capmatinib tablets)
- Zykadia (ceritinib hard-gelatin capsules)
- Xalkori (crizotinib)
- Cyramza (ramucirumab solution for intravenous infusion)
- Tafinlar (dabrafenib capsules)
- Vizimpro (dacomitinib)
- Taxotere (docetaxel for injection)
- Imfinzi (durvalumab injection)
- Rozlytrek (entrectinib capsules)
- Tarceva (erlotinib)
- Exkivity (mobocertinib capsules)
- Iressa (gefitinib)
- Gemzar (gemcitabine hcl)
- Infugem (gemcitabine in sodium chloride injection)
- Keytruda (pembrolizumab for injection)
- Mekinist (trametinib tablets)
- Portrazza (necitumumab intravenous injection)
- Opdivo (nivolumab injection)
- Tagrisso (osimertinib tablets)