Drug details

Prometrium (progesterone)

type of Progestins

Prometrium (progesterone) is a progestin, a female hormone, prescribed for the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women receiving conjugated estrogens tablets and also for secondary amenorrhea. Prometrium is available as a generic drug.

This drug may have the following side effects:
  • nausea,
  • upper stomach pain,
  • loss of appetite,
  • itching,
  • shortness of breath,
  • confusion,
  • rapid breathing,
  • tiredness,
  • clay-colored stools,
  • yellowing of the skin or eyes (jaundice),
  • severe headache,
  • wheezing,
  • sweating,
  • weakness,
  • chest pain or pressure,
  • pain behind the eyes,
  • mood changes,
  • dark colored urine,
  • sudden numbness or weakness,
  • drowsiness,
  • depression,
  • coughing up blood,
  • spinning sensation,
  • pain spreading to the jaw or shoulder,
  • pain or burning when urinating,
  • severe dizziness,
  • unusual vaginal bleeding,
  • sudden vision problems,
  • sudden severe headache,
  • sleep problems,
  • breast lump,
  • slurred speech ,
  • difficulty talking or balancing,
  • sudden cough ,
  • leg pain,
  • swelling in the leg, and
  • warmth or redness in one or both legs
The following drugs are related to Prometrium, either as a replacement or used together:
  • Activella (estradiol, norethindrone acetate)
  • Climara (estradiol transdermal)
  • Premarin (conjugated estrogens)
  • Prempro, Premphase (conjugated estrogens, medroxyprogesterone acetate)
  • Estratest (esterified estrogens and methyltestosterone)
  • Estrace (estradiol)
  • Estraderm (estradiol transdermal)
  • Femring (estradiol acetate)
  • Mimvey (estradiol and norethindrone acetate tablets)
  • Menostar (estradiol transdermal system)