Drug details

Vonjo (pacritinib capsules)

type of Antineoplastic Tyrosine Kinase Inhibitors

Vonjo (pacritinib) is a kinase inhibitor indicated for the treatment of adults with intermediate or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis with a platelet count below 50 × 109/L.

This drug may have the following side effects:
  • nausea,
  • lightheadedness,
  • sore throat
  • diarrhea,
  • chest pain or pressure,
  • cold sweat,
  • fever, and
  • hives, 
  • difficulty breathing, 
  • swelling of your face, lips, tongue, or throat, 
  • easy bruising, 
  • confusion, 
  • severe dizziness, 
  • fatigue,
  • fluttering in your chest, 
  • lack of coordination,
  • difficulty speaking,
  • any bleeding that will not stop. 
  • unusual bleeding,  
  • fainting,  
  • rapid or irregular heartbeats, 
  • wheezing,  
  • tightness or pain in the chest that may spread to your neck, jaw or back,
  • sudden numbness or weakness in an arm or leg (especially on one side of the body), 
  • difficulty understanding speech, 
  • sudden trouble seeing in one or both eyes,
  • sudden trouble walking, 
  • loss of balance, 
  • pain, warmth, or swelling in one leg,
  • change in your mental state,  
  • a growth or lump on your skin, 
The following drugs are related to Vonjo, either as a replacement or used together:
  • Inrebic (fedratinib capsules)
  • Ojjaara (momelotinib tablets)