Drug details

Osphena (ospemifene tablets)

type of Selective Estrogen Receptor Modulators

Osphena (ospemifene) is an estrogen agonist/antagonist prescribed for painful intercourse (dyspareunia), which is a symptom of vulvar and vagina muscular wasting (vaginal atrophy), due to menopause.

This drug may have the following side effects:
  • itching,
  • rash,
  • shortness of breath,
  • confusion,
  • rapid breathing,
  • fainting,
  • unusual sweating,
  • weakness on one side of the body,
  • trouble breathing
  • sudden dizziness,
  • trouble speaking,
  • swelling of the face, tongue, or throat, and
  • chest, jaw, and left arm pain,
  • sudden vision changes,
  • sudden severe headaches,
  • pain, swelling or warmth in growing or calf,
The following drugs are related to Osphena, either as a replacement or used together:
  • Cenestin (synthetic conjugated estrogens)
  • Premarin (conjugated estrogens)
  • Premarin Injection (conjugated estrogens for injection)
  • Premarin Vaginal Cream (conjugated estrogens vaginal cream)
  • Estratest (esterified estrogens and methyltestosterone)
  • Estrace (estradiol)
  • Estrace Vaginal Cream (estradiol vaginal cream)
  • Estraderm (estradiol transdermal)
  • EstroGel (estradiol gel)
  • Estring (estradiol vaginal ring)
  • Vagifem (estradiol vaginal tablets)
  • Menest (estrogens)
  • Estrostep 21 (norethindrone acetate-ethinyl estradiol-ferrous fumarate)
  • Estrostep Fe (norethindrone acetate-ethinyl estradiol-ferrous fumarate)
  • Veozah (fezolinetan tablets)
  • Fyavolv (norethindrone acetate and ethinyl estradiol tablets)