Drug details

Opana ER (oxymorphone hydrochloride extended release)

type of Opioid Analgesics

Opana ER (oxymorphone hydrochloride) is a narcotic pain reliever used to treat moderate to severe pain. The extended-release form of Opana is for around-the-clock treatment of pain. Opana ER is available in generic form.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • loss of appetite,
  • vomiting,
  • fever,
  • lightheadedness,
  • chest pain,
  • dizziness,
  • seizure,
  • diarrhea
  • wheezing,
  • sweating,
  • weakness,
  • agitation,
  • shivering,
  • hallucinations,
  • twitching,
  • fast heart rate,
  • weak or shallow breathing,
  • blue colored lips,
  • difficulty to wake up,
  • muscle stiffness,
  • loss of coordination, and
  • slow breathing with long pauses,
  • breathing that stops during sleep,
  • cough with yellow or green mucus,
  • severe vomiting,
  • worsening tiredness, 
The following drugs are related to Opana ER, either as a replacement or used together:
  • Arymo ER (morphine sulfate extended-release tablets)
  • Avinza (morphine sulfate)
  • Trilisate (choline magnesium trisalicylate)
  • Cytotec (misoprostol)
  • Duragesic (fentanyl transdermal)
  • Lodine (etodolac)
  • Nalfon (fenoprofen calcium)
  • Fentora (fentanyl buccal tablet)
  • Vantrela ER (hydrocodone)
  • Vicoprofen (hydrocodone and ibuprofen)
  • Reprexain Tablets (hydrocodone bitartrate and ibuprofen)
  • Savella (milnacipran hcl tablets)
  • Mitigo (morphine sulfate injection)
  • Nortriptyline Hydrochloride (nortriptyline hydrochloride capsules)
  • Qdolo (tramadol hydrochloride oral solution)
  • Ultram (tramadol hcl)
  • Ultram ER (tramadol hcl extended-release)
  • Ultracet (tramadol hydrochloride and acetaminophen tablets)