Drug details

Zofran (ondansetron hydrochloride tablets and solution)

type of Antiemetics, Selective 5-HT3 Antagonist

Zofran (ondansetron) is an antiemetic and selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting due to cancer chemotherapy and also used to prevent and treat nausea and vomiting after surgery. Zofran is available in generic form.

This drug may have the following side effects:
  • rash,
  • diarrhea,
  • fever,
  • lightheadedness,
  • tiredness,
  • dizziness,
  • constipation,
  • headache,
  • severe itching,
  • weakness,
  • drowsiness,
  • blurred vision, and
  • anxiety
  • urinary retention,
  • muscle spasm.
  • malaise/fatigue,
  • gynecologic disorder,
  • elevated liver function test results
The following drugs are related to Zofran, either as a replacement or used together:
  • Campral (acamprosate calcium)
  • Barhemsys (amisulpride injection, for intravenous use)
  • Emend Capsules (aprepitant capsules)
  • Bonjesta Extended-Release Tablets (doxylamine succinate and pyridoxine hydrochloride)
  • Emend Injection (fosaprepitant dimeglumine injection)
  • Focinvez (fosaprepitant injection)
  • Istodax (romidepsin for injection)
  • Zuplenz (ondansetron oral soluble film)
  • Varubi (rolapitant tablets)
  • Yondelis (trabectedin for injection)
The following supplements are related to Zofran, and may be used together with the drug:
  • Melatonin (s.)
  • Adenosine (s.)
  • Coriolus Mushroom (s.)
  • Artichoke (s.)
  • Ginger (s.)
  • Ipecac (s.)