Drug details

Paxlovid (nirmatrelvir tablets and ritonavir tablets)

type of Antivirals, Other, SARS-CoV-2 Antivirals

Paxlovid (nirmatrelvir tablets; ritonavir tablets) is an unapproved product that contains a SARS-CoV-2 main protease (Mpro: also referred to as 3CLpro or nsp5 protease) inhibitor and an HIV-1 protease inhibitor and CYP3A inhibitor issued under Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration for the treatment of mild-to-moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients (12 years of age and older weighing at least 40 kg) with positive results of direct severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral testing, and who are at high risk for progression to severe COVID-19, including hospitalization or death.

The drug is often used to treat HIV .

This drug may have the following side effects:

• severe dizziness, and
• hives, 
• difficulty breathing, 
• swelling of your face, lips, tongue, or throat, 
• abnormal lab test results 

The following drugs are related to Paxlovid, either as a replacement or used together:

• Bebtelovimab (bebtelovimab)
• Regen-Cov (casirivimab and imdevimab injection)
• Pfizer Biontech COVID-19 Vaccine (covid-19 vaccine)
• Moderna COVID-19 Vaccine (covid-19 vaccine)
• Novavax (covid-19 vaccine for intramuscular injection)
• Evusheld (tixagevimab injection; cilgavimab injection, copackaged for intramuscular use)
• Gohibic (vilobelimab injection)
• Lagevrio (molnupiravir)
• Veklury (remdesivir for injection)
• Xevudy (sotrovimab injection)