Drug details

Tysabri (natalizumab)

type of Inflammatory Bowel Disease Agents, Monoclonal Antibodies, Integrin Blockers

Tysabri (natalizumab) is a monoclonal antibody used in to treat relapsing forms of multiple sclerosis. Tysabri is also used to treat moderate to severe Crohn's disease in adults. Tysabri is usually given after other Crohn's disease medications have been tried without successful treatment of this condition.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • upper stomach pain,
  • loss of appetite,
  • itching,
  • dark urine,
  • clay-colored stools, and
  • yellowing of the skin or eyes (jaundice)
  • lightheadedness,
  • confusion,
  • chills,
  • tiredness,
  • chest pain,
  • dizziness,
  • severe headache,
  • wheezing,
  • vision changes,
  • eye pain,
  • memory problems,
  • pain or burning when urinating,
  • redness of the eye,
  • cough with yellow or green mucus,
  • sudden fever,
  • cold,
  • weakness on one side of your body,
  • changes in your mental state,
  • sweaty,
  • problems with your speech or walking,
  • trouble using your arms and legs,
The following drugs are related to Tysabri, either as a replacement or used together:
  • Ampyra (dalfampridine extended-release tablets)
  • Aubagio (teriflunomide tablets)
  • Avonex (interferon beta-1a)
  • Avsola (infliximab-axxq for injection)
  • Lyvispah (baclofen oral granules)
  • Ozobax (baclofen oral solution)
  • Bafiertam (monomethyl fumarate delayed-release capsules)
  • Betaseron (interferon beta-1b)
  • Ortikos (budesonide extended-release capsules)
  • Mavenclad (cladribine tablets)
  • Zinbryta (daclizumab for injection)
  • Dantrium Capsules (dantrolene sodium capsules)
  • Dantrium IV (dantrolene sodium for injection)
  • Tecfidera (dimethyl fumarate delayed release capsules)
  • Vumerity (diroximel fumarate delayed-release capsules)
  • Elzonris (tagraxofusp-erzs injection)
  • Extavia (interferon beta-1b kit)
  • Gilenya (fingolimod capsules)
  • Tascenso ODT (fingolimod orally disintegrating tablets)
  • Glatopa (glatiramer acetate injection)
  • H.P. Acthar Gel (repository corticotropin injection)
  • Rebif (interferon beta-1a)
  • Kesimpta (ofatumumab injection)
  • Mayzent (siponimod tablets)
  • Novantrone (mitoxantrone for injection concentrate)
  • Tyruko (natalizumab-sztn injection)
  • Ocrevus (ocrelizumab injection)
  • Zeposia (ozanimod capsules)
  • Pediapred (prednisolone sodium)
  • Plegridy (peginterferon beta-1a injection for subcutaneous use)
  • Triesence (triamcinolone acetonide injectable suspension)
The following supplements are related to Tysabri, and may be used together with the drug:
  • Marijuana (s.)
  • Superoxide Dismutase (s.)