Drug details

Opvee (nalmefene nasal spray)

type of Opioid Antagonists, Opioid Reversal Agents

Opvee (nalmefene) nasal spray is an opioid antagonist indicated for the emergency treatment of known or suspected overdose induced by natural or synthetic opioids in adults and pediatric patients aged 12 years and older, as manifested by respiratory and/or central nervous system depression.

This drug may have the following side effects:
  • nausea,
  • vomiting,
  • dizziness,
  • headache,
  • fatigue,
  • anxiety,
  • changes in taste,
  • decreased appetite,
  • throat irritation,
  • nasal congestion,
  • nasal discomfort,
  • hot flushes,
  • nasal pain,
  • redness, and
  • increased sweating.
The following drugs are related to Opvee, either as a replacement or used together:
  • Belbuca (buprenorphine buccal film)
  • Brixadi (buprenorphine extended-release injection)
  • Buprenex (buprenorphine)
  • Sublocade (buprenorphine injection for subcutaneous use)
  • Butrans (buprenorphine transdermal)
  • Narcan (naloxone hydrochloride injection)
  • Narcan Nasal (naloxone hydrochloride nasal spray)
  • Revia (naltrexone)
  • Vivitrol (naltrexone xr inj)