Drug details

Solu Medrol (methylprednisolone sodium succinate)

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Solu-Medrol (methylprednisolone) is a synthetic corticosteroid used for severe or incapacitating allergic conditions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, rheumatic disorders, and several other conditions. Generic formulations of Solu-Medrol are available.

This drug may have the following side effects:
  • nausea,
  • headache,
  • dizziness,
  • vomiting,
  • weight gain,
  • increased sweating,
  • trouble sleeping,
  • heartburn,
  • acne,
  • high blood sugar (hyperglycemia),
  • appetite changes,
  • fluid retention, 
  • muscle weakness, 
  • high blood pressure,
  • potassium loss,
  • convulsions,
  • cataracts,
  • glaucoma,
  • irregular menstrual periods,
  • injection site reactions (pain, redness, or swelling).
  • puffiness of the face,
  • hair growth on the face,
  • thinning and easy bruising of the skin,
  • peptic ulcers,
  • growth retardation in children,
  • psychiatric disturbances, and
The following drugs are related to Solu Medrol, either as a replacement or used together:
  • Benlysta (belimumab)
  • TaperDex (dexamethasone tablets)
  • gamaSTAN (immune globulin (human) for injection)
  • Prednisone (prednisone tablets, usp)