Drug details

Nucala (mepolizumab for injection)

type of Interleukin Inhibitors

Nucala (mepolizumab) is an interleukin-5 (IL-5) antagonist monoclonal antibody (IgG1 kappa) indicated for add-on maintenance treatment of patients with severe asthma aged 6 years and older, and with an eosinophilic phenotype; the treatment of adult patients with eosinophilic granulomatosis with polyangiitis (EGPA); and the treatment of adult and pediatric patients aged 12 years and older with hypereosinophilic syndrome (HES) for 6 or more months without an identifiable non-hematologic secondary cause.

The drug is often used to treat Asthma .

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • itching,
  • skin rash,
  • lightheadedness,
  • confusion,
  • chest pain,
  • dizziness,
  • blurred vision,
  • fainting,
  • sweating,
  • cough,
  • noisy breathing,
  • fast heartbeat,
  • weakness
  • unusual tiredness, and
  • redness of the skin,
  • painful blisters on the trunk of the body,
The following drugs are related to Nucala, either as a replacement or used together:
  • Accolate (zafirlukast)
  • Airsupra (albuterol and budesonide inhalation aerosol, for oral inhalation)
  • Proair Digihaler (albuterol sulfate inhalation powder)
  • Albuterol Sulfate Tablets (albuterol sulfate tablets)
  • Alvesco (ciclesonide inhalation aerosol)
  • Azmacort (triamcinolone acetonide (inhalation aerosol))
  • Pulmicort Turbuhaler (budesonide)
  • Symbicort (budesonide and formoterol fumarate dihydrate)
  • Pulmicort Flexhaler (budesonide inhalation powder)
  • Pulmicort Respules (budesonide inhalation suspension)
  • Dulera (mometasone furoate, formoterol fumarate dihydrate inhalation)
  • Flovent (fluticasone propionate)
  • Flovent Diskus (fluticasone propionate)
  • Flovent HFA (fluticasone propionate hfa)
  • Foradil Aerolizer (formoterol fumarate inhalation powder)
  • Foradil Certihaler (formoterol fumarate inhalation powder)
  • Singulair (montelukast sodium)
  • Xolair (omalizumab)