Drug details

Provera (medroxyprogesterone acetate tablets)

type of Progestins

Provera (medroxyprogesterone) is a form of the female hormone progesterone used to treat secondary amenorrhea; abnormal bleeding from the uterus due to hormonal imbalance and not due to fibroids, or cancer; and to prevent endometrial hyperplasia in postmenopausal women who have not undergone a hysterectomy and are receiving conjugated estrogens. Provera is used for contraception and for treating endometrial or renal cancer. A generic version of Provera is available.

This drug may have the following side effects:
  • nausea,
  • itching,
  • skin rash,
  • fever,
  • stomach pain,
  • hives, 
  • changes in appetite,
  • vaginal itching or discharge,
  • bloating,
  • loss of scalp hair,
  • changes in menstrual periods,
  • increased acne,
  • breast tenderness or discharge,
  • hair growth,
  • spotting or break-through bleeding,
  • increased or decreased weight,
  • sleep problems (insomnia), and
  • jaundice (yellowing of the skin or eyes), or
  • skin color changes.
The following drugs are related to Provera, either as a replacement or used together:
  • Actonel (risedronate sodium)
  • Amabelz (estradiol and norethindrone acetate tablets)
  • Cenestin (synthetic conjugated estrogens)
  • Premarin (conjugated estrogens)
  • Prolia (denosumab injection)
  • Safyral (drospirenone/ethinyl estradiol/levomefolate calcium tablets and levomefolate)
  • Estratest (esterified estrogens and methyltestosterone)
  • Estrace (estradiol)
  • Estraderm (estradiol transdermal)
  • EstroGel (estradiol gel)
  • Estring (estradiol vaginal ring)
  • Ogen (estropipate)
  • Evista (raloxifene)