Drug details

Margenza (margetuximab-cmkb injection, for intravenous use)

type of Antineoplastics, Anti-HER2

Margenza (margetuximab-cmkb) is a HER2/neureceptor antagonist indicated, in combination with chemotherapy, to treat adult patients with metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens, at least one of which was for metastatic disease.

This drug may have the following side effects:
  • nausea,
  • vomiting,
  • diarrhea,
  • fever,
  • shortness of breath,
  • constipation,
  • headache,
  • fatigue,
  • weakness,
  • cough,
  • abdominal pain,
  • hair loss,
  • infusion-related reactions,
  • joint or muscle pain,
  • decreased appetite,
  • numbness and tingling in extremities,
  • hand-foot syndrome (palmar-plantar erythrodysesthesia), and
  • extremity pain
The following drugs are related to Margenza, either as a replacement or used together:
  • Kadcyla (ado-trastuzumab emtansine injection for iv use)
  • Afinitor (everolimus tablets)
  • Afinitor Disperz (everolimus tablets)
  • Aredia (pamidronate disodium)
  • Aromasin (exemestane)
  • Ellence (epirubicin hydrochloride)
  • Enhertu (fam-trastuzumab deruxtecan-nxki for injection)
  • Halaven Injection (eribulin mesylate)
  • Fareston (toremifene)
  • Faslodex (fulvestrant)
  • Femara (letrozole)
  • Infugem (gemcitabine in sodium chloride injection)
  • Ixempra (ixabepilone)
  • Keytruda (pembrolizumab for injection)
  • Lynparza (olaparib capsules for oral administration)
  • Nerlynx (neratinib tablets)
  • Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf injection)
  • Trodelvy (sacituzumab govitecan-hziy for injection, for iv use)
  • Soltamox (tamoxifen citrate)