Drug details

Twirla (levonorgestrel and ethinyl estradiol transdermal system)

type of Contraceptives, Transdermal

Twirla (levonorgestrel and ethinyl estradiol) is a combination of the female hormones progestin and estrogen used as a method of contraception for use in women of reproductive potential with a BMI less than 30 kg/m2 for whom a combined hormonal contraceptive is appropriate.

This drug may have the following side effects:
  • nausea,
  • headache,
  • weight gain
  • menstrual cramps, and
  • aprepitant,
  • barbiturates,
  • bosentan,
  • carbamazepine,
  • efavirenz,
  • felbamate,
  • griseofulvin,
  • oxcarbazepine,
  • phenytoin,
  • rifampin,
  • rifabutin,
  • rufinamide,
  • topiramate,
  • St. John's wort,
  • protease inhibitors,
  • colesevelam
  • atorvastatin or rosuvastatin,
  • ascorbic acid,
  • acetaminophen,
  • itraconazole,
  • voriconazole,
  • fluconazole,
  • ketoconazole,
  • grapefruit juice,
  • thyroid hormone,
  • cortisol therapy,
  • morphine,
  • salicylic acid,
  • temazepam,
  • cyclosporine,
  • prednisolone,
  • theophylline, and
  • tizanidine
The following drugs are related to Twirla, either as a replacement or used together:
  • Annovera (segesterone acetate and ethinyl estradiol vaginal system)
  • Ortho-Cept (desogestrel and ethinyl estradiol tablets)
  • Yaz (drospirenone and ethinyl estradiol)
  • Loryna (drospirenone and ethinyl estradiol tablets)
  • Errin (norethindrone tablets usp)
  • NuvaRing (etonogestrel, ethinyl estradiol vaginal ring)
  • Mirena (levonorgestrel-releasing intrauterine system)
  • Liletta (levonorgestrel-releasing intrauterine system)
  • Ortho Evra (norelgestromin, ethinyl estradiol transdermal)
  • Ortho Micronor (norethindrone)
  • Taytulla (norethindrone acetate-ethinyl estradiol-ferrous fumarate)
  • Ortho-Novum (norethindrone and ethinyl estradiol)
  • Ortho Tri-Cyclen / Ortho-Cyclen (norgestimate and ethinyl estradiol)
  • Ortho Tri-Cyclen Lo (norgestimate, ethinyl estradiol)