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Drug details

Lupron (leuprolide acetate injection)

type of How Do Antineoplastic GNRH Agonists Work?

Lupron Injection (leuprolide acetate) is a synthetic gonadotropin-releasing hormone used in men to treat symptoms of prostate cancer, and in women to treat symptoms of endometriosis (overgrowth of uterine lining outside of the uterus) or uterine fibroids. Lupron Injection is also used to treat precocious (early-onset) puberty in both male and female children.

The drug is often used to treat Endometriosis , Prostate cancer .

This drug may have the following side effects:
  • nausea,
  • headache,
  • dizziness,
  • diarrhea,
  • weakness,
  • constipation,
  • chills,
  • stomach pain,
  • upset stomach,
  • trouble sleeping (insomnia),
  • tiredness,
  • depression,
  • increased sweating,
  • skin redness,
  • acne,
  • redness/burning/stinging/pain/bruising at the injection site,

  • hot flashes (flushing),

  • night sweats,
  • breast swelling or tenderness,
  • joint/muscle aches or pain,
  • reduced sexual interest,
  • vaginal discomfort/dryness/itching/discharge,

  • vaginal bleeding,
  • swelling of the ankles/feet,
  • increased urination at night,
  • breakthrough bleeding in a female child during the first 2 months of leuprolide treatment,
  • clammy skin,
  • itching or
    scaling,
  • testicle pain,

  • impotence,
  • increased growth of facial hair, or
  • memory problems.
The following drugs are related to Lupron, either as a replacement or used together:
  • Tymlos (abaloparatide injection)
  • Plenaxis (abarelix)
  • Zytiga (abiraterone acetate tablets)
  • Alkeran (melphalan)
  • Axumin (fluciclovine f 18 intravenous injection)
  • Vidaza (azacitidine)
  • Casodex (bicalutamide)
  • Firmagon (degarelix for injection)
  • Xgeva (denosumab)
  • Dexferrum (iron dextran injection, usp)
  • Eligard (leuprolide acetate)
  • Emcyt (estramustine)
  • Xtandi (enzalutamide capsules)
  • Fensolvi (leuprolide acetate for injectable suspension, for subcutaneous use)
  • Feraheme (ferumoxytol injection)
  • Injectafer (ferric carboxymaltose injection)
  • Zoladex 10.8 mg (goserelin acetate implant)
  • Zoladex 3.6 (goserelin acetate implant)
  • Vantas (histrelin acetate)
  • Venofer (iron sucrose injection)
  • Lupron Depot 11.25 mg (leuprolide acetate for depot suspension)
  • Lupron Depot 7.5 mg (leuprolide acetate for depot suspension)
  • Lupron Depot (leuprolide acetate for depot suspension)
  • Lutrate Depot (leuprolide acetate for depot suspension)
  • Lupron Depot-Ped (leuprolide acetate for depot suspension)
  • Lupron Depot 22.5 (leuprolide acetate for depot suspension injection)
  • Lupaneta Pack (leuprolide acetate for depot suspension; norethindrone acetate tablets)
  • Viadur (leuprolide acetate implant)
  • Lupron Depot 3.75 mg (leuprolide acetate injection)
  • Omontys (peginesatide)
  • Provenge (sipuleucel-t suspension for intravenous infusion)
  • Xofigo (radium ra 223 dichloride)
  • Trelstar (triptorelin pamoate for injectable suspension)
  • Trelstar Depot (triptorelin pamoate for injectable suspension)
  • Trelstar LA (triptorelin pamoate for injectable suspension)
The following supplements are related to Lupron, and may be used together with the drug:
  • Selenium (s.)
  • Strontium (s.)
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