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Drug details

Kombiglyze XR (saxagliptin and metformin hcl extended-release)

type of Antidiabetics, Dipeptyl Peptidase-IV Inhibitors, Antidiabetics, Biguanides

Kombiglyze XR (saxagliptin and metformin hydrochloride) Extended-release Tablets is a combination drug indicated, along with diet and exercise, as a treatment for type 2 diabetes in adults. Kombiglyze XR is NOT indicated for use in type 1 diabetics or diabetic ketoacidosis. Kombiglyze XR is a combination of two prescription medications called saxagliptin and metformin hydrochloride that are available as generic drugs.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • loss of appetite,
  • itching,
  • vomiting,
  • lightheadedness,
  • shortness of breath,
  • fast heartbeats,
  • tiredness,
  • stomach pain,
  • dizziness,
  • weakness,
  • feeling cold,
  • pain or burning when you urinate,
  • severe pain in your upper stomach spreading to your back,
  • blisters,
  • rapid weight gain
  • unusual muscle pain,
  • irregular heart rate,
  • peeling skin,
  • swelling in your legs or feet, and
  • breakdown of the outer layer of skin,
  • severe or ongoing pain in your joints,
The following drugs are related to Kombiglyze XR, either as a replacement or used together:
  • Precose (acarbose)
  • Amaryl Tablets (glimepiride)
  • Zegalogue (dasiglucagon injection)
  • Trijardy XR (empagliflozin, linagliptin, and metformin hydrochloride extended-release tablets)
  • Glucotrol (glipizide)
  • Glucotrol XL (glipizide extended release)
  • GlucaGen (glucagon [rdna origin]) for injection)
  • Glucophage, Glucophage XR (metformin hcl)
  • Glucovance (glyburide and metformin)
  • Glumetza (metformin hcl)
  • Glynase PresTab (micronized glyburide tablets)
  • NovoLog (insulin aspart [rdna origin] inj)
  • NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart (rdna origin))
  • Toujeo (insulin glargine injection for subcutaneous use)
  • Lyumjev (insulin lispro-aabc injection)
  • NovoLog Mix 50/50 (50% insulin aspart protamine suspension and 50% insulin aspart injection)
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