Drug details

Kcentra (prothrombin complex concentrate (human))

type of Hemostatics, Blood Components

Kcentra Prothrombin Complex Concentrate (Human) contains the Vitamin K dependent Coagulation Factors II, VII, IX and X, and the antithrombotic Proteins C and S and is used for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.

This drug may have the following side effects:

• nausea,
• vomiting,
• joint pain,
• headache,
• low blood pressure (hypotension), and
• low levels of iron in the blood (anemia)

The following drugs are related to Kcentra, either as a replacement or used together:

• Balfaxar (prothrombin complex concentrate, human-lans)
• Bebulin VH (factor ix complex intravenous administration)
• Profilnine (factor ix complex intravenous administration)