Drug details

Jynarque (tolvaptan tablets for oral use)

type of Vasopressin Antagonists

Jynarque (tolvaptan) is a selective vasopressin V2-receptor antagonist indicated to slow kidney function decline in adults at risk of rapidly progressing autosomal dominant polycystic kidney disease (ADPKD).

This drug may have the following side effects:
  • rash,
  • indigestion,
  • dry skin,
  • bloating,
  • thirst,
  • heart palpitations
  • decreased appetite,
  • nighttime urination,
  • increased urination (both in volume and frequency),
  • high uric acid in the blood, and
The following drugs are related to Jynarque, either as a replacement or used together:
  • Kerendia (finerenone tablets)
  • Glofil-125 (sodium iothalamate i-125 injection solution)