Drug details

Jentadueto XR (linagliptin and metformin hydrochloride extended-release tablets)

type of Antidiabetics, Biguanides/Dipeptyl Peptidase-IV Inhibitors

Jentadueto XR (linagliptin and metformin hydrochloride extended-release) is a dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide combination product indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both linagliptin and metformin is appropriate. Jentadueto XR is not for treatment of type 1 diabetes or diabetic ketoacidosis.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • loss of appetite,
  • itching,
  • vomiting,
  • fever,
  • shortness of breath,
  • fast heartbeats,
  • tiredness,
  • stomach pain,
  • dizziness,
  • weakness,
  • sore throat,
  • burning eyes,
  • skin pain,
  • red or purple skin rash with blistering and peeling,
  • feeling cold,
  • rapid weight gain
  • unusual muscle pain,
  • swelling in your legs or feet, and
  • breakdown of the outer layer of skin,
  • severe or ongoing pain in your joints,
  • fast, slow or irregular heartbeats,
  • blistering,
The following drugs are related to Jentadueto XR, either as a replacement or used together:
  • Avandia (rosiglitazone maleate)
  • Invokana (canagliflozin tablets)
  • Zegalogue (dasiglucagon injection)
  • Glucotrol XL (glipizide extended release)
  • Glucovance (glyburide and metformin)
  • Lyumjev (insulin lispro-aabc injection)
  • Januvia (sitagliptin phosphate)
  • Tradjenta (linagliptin)
  • Saxenda (liraglutide [rdna origin]) injection)
  • Victoza (liraglutide [rdna] injection)
  • Starlix Tablet (nateglinide)
  • Symlin (pramlintide acetate injection)
  • Prandin (repaglinide)
  • Tolinase (tolbutamide tablets)