Drug details

Jakafi (ruxolitinib)

type of DMARDs, JAK Inhibitors

Jakafi (ruxolitinib) is a kinase inhibitor used in the treatment of intermediate or high-risk types of myelofibrosis, a potentially life-threatening blood cancer

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • loss of appetite,
  • vomiting,
  • fever,
  • night sweats,
  • easy bruising,
  • unusual bleeding,
  • pale skin,
  • lightheadedness,
  • shortness of breath,
  • cold hands and feet,
  • chills,
  • tiredness,
  • weakness,
  • cough,
  • mouth sores,
  • pain or burning when you urinate,
  • skin sores,
  • general ill feeling,
  • weight loss, and
  • problems with speech, thought, vision, or muscle movement,
  • blisters or painful skin rash,
  • changes in the size, shape, or color of a mole or skin lesion,
  • feeling very tired
The following drugs are related to Jakafi, either as a replacement or used together:
  • Campath (alemtuzumab)
  • Trisenox (arsenic trioxide injection)
  • Rezurock (belumosudil tablets)
  • BESREMi (ropeginterferon alfa-2b-njft)
  • Blincyto (blinatumomab for injection)
  • Busulfex (busulfan)
  • Leustatin (cladribine injection for intravenous infusion only)
  • Cytoxan (cyclophosphamide)
  • Sprycel (dasatinib)
  • Decadron (dexamethasone)
  • Elzonris (tagraxofusp-erzs injection)
  • Toposar (etoposide injection)
  • Inrebic (fedratinib capsules)
  • Zarxio (filgrastim-sndz injection)
  • Fludara (fludarabine)
  • Mylotarg (gemtuzumab ozogamicin for injection)
  • Gleevec (imatinib mesylate)
  • Idamycin (idarubicin)
  • Idamycin PFS (idarubicin hydrochloride injection)
  • Purinethol (mercaptopurine)
  • Ojjaara (momelotinib tablets)
  • Vesanoid (tretinoin)
  • Valtrex (valacyclovir hydrochloride)