Drug details

Istodax (romidepsin for injection)

type of Antineoplastics HDAc Inhibitors

Istodax (romidepsin) for Injection is a histone deacetylase (HDAC) inhibitor used to treat T-cell lymphoma affecting the skin (cutaneous T-cell lymphoma, or CTCL). Istodax is usually given after other medications have been tried without successful treatment of symptoms.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • vomiting,
  • fever,
  • easy bruising,
  • unusual bleeding,
  • pale skin,
  • lightheadedness,
  • shortness of breath,
  • cold hands and feet,
  • chills,
  • tiredness,
  • chest pain,
  • fluttering in your chest,
  • muscle aches,
  • weakness,
  • cough,
  • flu symptoms,
  • mouth sores,
  • muscle cramps,
  • sudden dizziness,
  • skin sores,
  • tingling in your hands and feet or around your mouth
  • diarrhea, and
  • chest congestion,
  • burning when you urinate,
  • worsening skin symptoms,
  • fast, slow or pounding heartbeats,
The following drugs are related to Istodax, either as a replacement or used together:
  • Proleukin (aldesleukin for injection)
  • Campath (alemtuzumab)
  • Aloprim (allopurinol sodium for injection)
  • Emend Capsules (aprepitant capsules)
  • Targretin (bexarotene)
  • Targretin Gel (bexarotene gel)
  • Emend Injection (fosaprepitant dimeglumine injection)
  • Zynlonta (loncastuximab tesirine-lpyl for injection)
  • Zofran Injection (ondansetron hydrochloride injection)
  • Zofran (ondansetron hydrochloride tablets and solution)
  • Riabni (rituximab-arrx injection)
  • Ukoniq (umbralisib tablets)