Drug details

Sarclisa (isatuximab-irfc injection)

type of Antineoplastics, Anti-CD38 Monoclonal Antibodies

Sarclisa (isatuximab-irfc) is a CD38-directed cytolytic antibody used, in combination with pomalidomide and dexamethasone, to treat adult patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor

The drug is often used to treat Multiple myeloma .

This drug may have the following side effects:
  • diarrhea,
  • anemia,
  • low white blood cell count (neutropenia),
  • upper respiratory tract infection,
  • pneumonia,
  • infusion-related reactions (shortness of breath, high blood pressure, and bronchospasm),
  • low lymphocytes (lymphopenia), and
  • low platelets (thrombocytopenia)
The following drugs are related to Sarclisa, either as a replacement or used together:
  • Abecma (idecabtagene vicleucel suspension)
  • Adriamycin PFS (doxorubicin hydrochloride)
  • Aphexda (motixafortide for injection)
  • Treanda (bendamustine hydrochloride injection)
  • Carvykti (ciltacabtagene autoleucel for iv injection)
  • Cytoxan (cyclophosphamide)
  • Doxil (doxorubicin hcl liposome injection)
  • Empliciti (elotuzumab for injection)
  • Vincristine Sulfate Injection (vincristine sulfate)