Drug details

Ibrance (palbociclib capsules for oral administration)

type of Antineoplastics CDK Inhibitors

Ibrance (palbociclib) is a kinase inhibitor used in combination with letrozole for the treatment of postmenopausal women with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer as initial endocrine-based therapy for their metastatic disease.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • fever,
  • easy bruising,
  • unusual bleeding,
  • pale skin,
  • lightheadedness,
  • shortness of breath,
  • cold hands and feet,
  • chills,
  • chest pain,
  • dizziness,
  • wheezing,
  • weakness,
  • trouble swallowing,
  • mouth sores,
  • sudden cough,
  • new or worsening cough,
  • skin sores,
  • red or swollen gums,
  • rapid breathing, and
  • coughing up blood
  • blisters or ulcers in your mouth,
  • painful or difficult breathing,
The following drugs are related to Ibrance, either as a replacement or used together:
  • Abraxane (albumin-bound paclitaxel for injectable suspension)
  • Kadcyla (ado-trastuzumab emtansine injection for iv use)
  • Aredia (pamidronate disodium)
  • Aromasin (exemestane)
  • BiCNU (carmustine)
  • Xeloda (capecitabine)
  • Capecitabine (Xeloda) Tablets (capecitabine tablets)
  • Cytoxan (cyclophosphamide)
  • Delatestryl (testosterone enanthate)
  • Docefrez (docetaxel)
  • Taxotere (docetaxel for injection)
  • Ellence (epirubicin hydrochloride)
  • Elzonris (tagraxofusp-erzs injection)
  • Enhertu (fam-trastuzumab deruxtecan-nxki for injection)
  • Fareston (toremifene)
  • Faslodex (fulvestrant)
  • Femara (letrozole)
  • Halotestin (fluoxymesterone)
  • Zoladex 10.8 mg (goserelin acetate implant)
  • Herceptin (trastuzumab)
  • Herceptin Hylecta (trastuzumab and hyaluronidase-oysk injection, for subcutaneous use)
  • Herzuma (trastuzumab-pkrb for injection)
  • Ixempra (ixabepilone)
  • Tykerb (lapatinib)
  • Vanflyta (quizartinib tablets)
  • Trodelvy (sacituzumab govitecan-hziy for injection, for iv use)
  • Soltamox (tamoxifen citrate)
  • Talzenna (talazoparib capsules)
  • Tukysa (tucatinib tablets)