Drug details

Siklos (hydroxyurea tablets, for oral use)

type of Antineoplastics, Antimetabolite

Siklos (hydroxyurea) is an antimetabolite, indicated to reduce the frequency of painful crises and to reduce the need for blood transfusions in pediatric patients, 2 years of age and older, with sickle cell anemia with recurrent moderate to severe painful crises.

This drug may have the following side effects:

• hives,
• difficulty breathing,
• swelling of your face, lips, tongue, or throat,
• nausea,
• loss of appetite,
• yellowing of the skin or eyes (jaundice)
• vomiting,
• fever,
• easy bruising,
• unusual bleeding,
• pale skin,
• lightheadedness,
• shortness of breath,
• cold hands and feet,
• chills,
• tiredness,
• wheezing,
• mouth sores,
• dark urine, and
• fast heart rate,
• dry cough,
• numbness, tingling, or burning pain in your hands or feet,
• skin numbness or purple discoloration,
• sudden chest pain,
• upper stomach pain (that may spread to your back),
• skin ulcers or open sores,

The following drugs are related to Siklos, either as a replacement or used together:

• Oxbryta (voxelotor tablets)