Drug details

Makena (hydroxyprogesterone caproate injection)

type of Progestins

Makena (hydroxyprogesterone caproate) is a prescription hormone medicine (progestin) used in women who are pregnant with only one baby and who have delivered a premature baby in the past. Makena is used in these women to help lower the risk of having a preterm baby again. Makena is not intended for use to stop active preterm labor.

This drug may have the following side effects:
  • nausea,
  • diarrhea,
  • itching,
  • allergic reactions,
  • hives, 
  • blood clots,
  • high blood pressure (hypertension),
  • fluid retention, 
  • migraine,
  • injection site reactions (pain, bruising, itching, swelling, or a hard lump),