Drug details

Hyalgan (hyaluronate)

type of Rheumatologics, Other, Sodium hyaluronate

Hyalgan (sodium hyaluronate) is a synovial fluid replacement that works by acting as a lubricant and shock absorber in the joint used to treat knee pain in patients with joint inflammation (osteoarthritis). Hyalgan is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical therapy.

This drug may have the following side effects:

• nausea,
• headache,
• stomach pain,
• back pain,
• numbness or tingly feeling,
• cold symptoms (stuffy nose, sneezing, sore throat),
• injection site reactions (pain, swelling, redness, warmth, bruising, stiffness, or puffiness),
  
• tired feeling, or
• itching or skin irritation around the knee.

The following drugs are related to Hyalgan, either as a replacement or used together:

• Gel-One (cross-linked hyaluronate viscoelastic hydrogel)
• Hymovis (high molecular weight viscoelastic hyaluronan)
• Orthovisc (hyaluronan)