Drug details

Herceptin Hylecta (trastuzumab and hyaluronidase-oysk injection, for subcutaneous use)

type of Antineoplastics, Anti-HER2

Herceptin Hylecta (trastuzumab and hyaluronidase-oysk) is a combination of a HER2/neu receptor antagonist, and an endoglycosidase, indicated in adults for the treatment of HER2-overexpressing breast cancer.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • rash,
  • diarrhea,
  • fever,
  • lightheadedness,
  • shortness of breath,
  • chills,
  • rapid breathing,
  • tiredness,
  • chest pain,
  • dizziness,
  • fluttering in your chest,
  • wheezing,
  • trouble swallowing,
  • sore throat,
  • rapid weight gain,
  • lightheadedness
  • fast or pounding heartbeats,
  • new or worsening cough,
  • pain when you breathe,
  • skin sores,
  • red or swollen gums,
  • gasping for breath,
  • cold hands and feet, and
  • blisters or ulcers in your mouth,
  • swelling in your face or lower legs,
  • cough foamy mucus,
The following drugs are related to Herceptin Hylecta, either as a replacement or used together:
  • Verzenio (abemaciclib tablets)
  • Kadcyla (ado-trastuzumab emtansine injection for iv use)
  • Aredia (pamidronate disodium)
  • Aromasin (exemestane)
  • Ayvakit (avapritinib tablets)
  • Xeloda (capecitabine)
  • Halaven Injection (eribulin mesylate)
  • Evista (raloxifene)
  • Fareston (toremifene)
  • Faslodex (fulvestrant)
  • Femara (letrozole)
  • Gemzar (gemcitabine hcl)
  • Herceptin (trastuzumab)
  • Ibrance (palbociclib capsules for oral administration)
  • Ixempra (ixabepilone)
  • Kisqali (ribociclib tablets)
  • Kisqali FeMara Co-Pack (ribociclib and letrozole tablets)
  • Lynparza (olaparib capsules for oral administration)
  • Nerlynx (neratinib tablets)
  • Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf injection)
  • Trodelvy (sacituzumab govitecan-hziy for injection, for iv use)
  • Thiotepa (thiotepa injection)