Drug details

Simponi Injection (golimumab injection)

type of DMARDs, TNF Inhibitors, Monoclonal Antibodies, Antipsoriatics, Systemic, Inflammatory Bowel Disease Agents

Simponi (golimumab injection) is a human IgG1k monoclonal antibody used to treat rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. Simponi is sometimes used with another medication called methotrexate (Rheumatrex, Trexall). Simponi works by blocking a protein (tumor necrosis factor or TNF) found in the body's immune system that causes joint swelling and damage.

The drug is often used to treat Ankylosing spondylitis , Psoriatic arthritis .

This drug may have the following side effects:
  • loss of appetite,
  • dark urine,
  • diarrhea,
  • fever,
  • night sweats,
  • pale skin,
  • lightheadedness,
  • shortness of breath,
  • weight loss,
  • chills,
  • tiredness,
  • stomach pain,
  • clay-colored stools,
  • yellowing of the skin or eyes (jaundice),
  • cough,
  • sore throat,
  • increased urination,
  • mouth sores,
  • right-sided upper stomach pain,
  • vision changes,
  • coughing up blood,
  • skin sores,
  • muscle or joint pain,
  • easy bruising or bleeding,
  • warmth,
  • redness,
  • numbness or tingly feeling,
  • swelling of your ankles or feet,
  • weakness in your arms or legs,
  • burning pain when urinating,
  • skin growths,
  • changes in skin appearance,
  • skin rash on your cheeks or arms that worsens in sunlight, and
  • red or scaly patches of skin, flaking or pus
The following drugs are related to Simponi Injection, either as a replacement or used together:
  • Abrilada (adalimumab-afzb injection, for subcutaneous use)
  • Clanza CR (aceclofenac tablet, film coated)
  • Humira (adalimumab injection solution for subcutaneous administration)
  • Idacio (adalimumab-aacf injection)
  • Yusimry (adalimumab-aqvh injection)
  • Imraldi (adalimumab-xxxx injection, for subcutaneous use)
  • Kineret (anakinra)
  • Ansaid (flurbiprofen)
  • Arava (leflunomide)
  • Avinza (morphine sulfate)
  • Imuran (azathioprine)
  • Olumiant (baricitinib tablets)
  • Beser (fluticasone propionate lotion)
  • Colocort (hydrocortisone rectal suspension)
  • Cortaren (dexamethasone sodium phosphate injection)
  • Cytoxan (cyclophosphamide)
  • Sandimmune (cyclosporine)
  • Neoral (cyclosporine)
  • Zipsor (diclofenac potassium liquid filled capsules)
  • Voltaren (diclofenac sodium)
  • Duexis (ibuprofen and famotidine tablets)
  • Duobrii (halobetasol propionate and tazarotene lotion)
  • Eticovo (etanercept injection)
  • Lodine (etodolac)
  • Simponi Aria (golimumab for infusion)
  • Inflectra (infliximab-dyyb intravenous injection)
  • Kenalog 10 Injection (triamcinolone acetonide injectable suspension)
  • Kevzara (sarilumab injection, for subcutaneous use)
  • Morphabond (morphine sulfate extended-release tablets)
  • Rinvoq (upadacitinib extended-release tablets)
  • Skyrizi (risankizumab-rzaa injection)
  • Xeljanz (tofacitinib tablets)