Drug details

Iressa (gefitinib)

type of How Do Antineoplastic EGFR Inhibitors Work?

Iressa (gefitinib) is a tyrosine kinase inhibitor used for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test.

This drug may have the following side effects:

• vomiting,
• diarrhea,
• skin reactions,
• decreased appetite,
• nail disorders,
• inflammation of the mouth lining,
• eyelid swelling, and
• dry eye.

The following drugs are related to Iressa, either as a replacement or used together:

• Alecensa (alectinib capsules)
• Alimta (pemetrexed)
• Alkeran (melphalan)
• Alunbrig (brigatinib tablets)
• Amnesteem Capsules (isotretinoin)
• Tabrecta (capmatinib tablets)
• Claravis Capsules (isotretinoin)
• Cosela (trilaciclib for injection)
• Xalkori (crizotinib)
• Vizimpro (dacomitinib)
• Xgeva (denosumab)
• Tarceva (erlotinib)
• Exkivity (mobocertinib capsules)
• Hycamtin Capsules (topotecan capsules)
• Lumakras (sotorasib tablets)
• Tagrisso (osimertinib tablets)
• Retevmo (selpercatinib capsules)
• Tazverik (tazemetostat tablets)
• Tepmetko (tepotinib tablets)

The following supplements are related to Iressa, and may be used together with the drug:

• Melatonin (s.)
• Adenosine (s.)
• Coriolus Mushroom (s.)