Drug details

Fyarro (sirolimus protein-bound particles for injectable suspension)

type of Antineoplastics mTOr Kinase Inhibitors

Fyarro (sirolimus protein-bound particles for injectable suspension) (albumin-bound) is an mTOR inhibitor indicated for the treatment of adult patients with locally advanced unresectable or metastatic malignant perivascular epithelioid cell tumor (PEComa).

This drug may have the following side effects:
  • nausea,
  • vomiting,
  • diarrhea,
  • cough,
  • weight loss,
  • rash,
  • infection,
  • fatigue,
  • swelling and sores inside the mouth,
  • changes in taste,
  • decreased appetite,
  • musculoskeletal pain,
  • fluid retention (edema),
  • decreased lymphocytes, 
  • increased glucose, 
  • decreased potassium, 
  • decreased phosphate, 
  • decreased hemoglobin, and 
  • increased lipase. 
The following drugs are related to Fyarro, either as a replacement or used together:
  • Afinitor (everolimus tablets)
  • Afinitor Disperz (everolimus tablets)
  • Cosmegen (dactinomycin for injection)
  • Rozlytrek (entrectinib capsules)
  • Halaven Injection (eribulin mesylate)
  • Zortress (everolimus)
  • Tazverik (tazemetostat tablets)