Drug details

Subsys (fentanyl sublingual spray)

type of Opioid Analgesics

Subsys (fentanyl) sublingual spray is a potent opioid analgesic (pain reliever) indicated for the treatment of breakthrough cancer pain (BTCP) in opioid-tolerant adult patients who are already routinely taking other opioid pain medicines around-the-clock for cancer pain.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • loss of appetite,
  • vomiting,
  • fever,
  • lightheadedness,
  • confusion,
  • severe drowsiness,
  • dizziness,
  • diarrhea
  • sweating,
  • weakness,
  • agitation,
  • shivering,
  • slow heart rate,
  • shallow breathing,
  • hallucinations,
  • twitching,
  • unusual thoughts or behavior,
  • fast heart rate,
  • blue colored lips,
  • muscle stiffness,
  • loss of coordination, and
  • slow breathing with long pauses,
  • difficult to wake up,
  • sighing,
  • breathing that stops during sleep,
  • worsening tiredness,
  • extreme fear,
The following drugs are related to Subsys, either as a replacement or used together:
  • Actiq (fentanyl citrate)
  • Dilaudid (hydromorphone hydrochloride)
  • Dilaudid-HP (hydromorphone hydrochloride injection)
  • Fentora (fentanyl buccal tablet)
  • Fentanyl Citrate Injection (fentanyl citrate injection)
  • Vicodin (hydrocodone and acetaminophen)
  • Vicodin ES (hydrocodone bitartrate and acetaminophen)
  • Vicodin HP (hydrocodone bitartrate and acetaminophen tablets)
  • Percocet (oxycodone and acetaminophen)