Drug details

Femara (letrozole)

type of Antineoplastics Aromatase Inhibitor, How Do Antineoplastic CDK Inhibitors Work?

Femara (letrozole) is a non-steroidal aromatase inhibitor (lowers estrogen
production) used to treat breast cancer in postmenopausal women. Femara is often
given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.
Femara is available in generic form.

This drug may have the following side effects:

• nausea,
• headache,
• dizziness,
• diarrhea,
• weakness,
• constipation,
• flushing (warmth, redness, or tingly feeling),
• tiredness,
• drowsiness,
• weight gain,
• trouble sleeping,
• hair loss,
• hot flashes,
• joint/bone/muscle pain,
• warmth in your face or chest,
• unusual sweating or night sweats,
• numbness/tingling/weakness/stiffness in your hand or fingers, or
• pain in your hand that spreads to your arm, wrist, forearm, or shoulder.

The following drugs are related to Femara, either as a replacement or used together:

• ExEm Foam (air polymer-type a intrauterine foam)
• Aromasin (exemestane)
• Zirabev (bevacizumab-bvzr injection)
• Caelyx (pegylated liposomal doxorubicin hydrochloride injection)
• Totect (dexrazoxane for injection, intravenous infusion only)
• Docefrez (docetaxel)
• Enhertu (fam-trastuzumab deruxtecan-nxki for injection)
• Minivelle (estradiol transdermal system)
• Fareston (toremifene)
• Fentora (fentanyl buccal tablet)
• Herceptin (trastuzumab)
• Herceptin Hylecta (trastuzumab and hyaluronidase-oysk injection, for subcutaneous use)
• Ibrance (palbociclib capsules for oral administration)
• Jinteli (norethindrone acetate and ethinyl estradiol tablets, usp)
• Kanjinti (trastuzumab-anns for injection)
• Tykerb (lapatinib)
• Margenza (margetuximab-cmkb injection, for intravenous use)
• Megace (megestrol acetate)
• Megace ES (megestrol acetate)
• Milprosa (progesterone vaginal system)
• Nolvadex (tamoxifen citrate)
• Ontruzant (trastuzumab-dttb for injection)
• Paclitaxel Tablets (paclitaxel)
• Trodelvy (sacituzumab govitecan-hziy for injection, for iv use)
• Talzenna (talazoparib capsules)
• Trazimera (trastuzumab-qyyp for injection)

The following supplements are related to Femara, and may be used together with the drug:

• Folic Acid (s.)
• Olive (s.)
• Vitamin A (s.)
• Beta-Carotene (s.)