Drug details

Exkivity (mobocertinib capsules)

type of Antineoplastics EGFR Inhibitors

Exkivity (mobocertinib) is a kinase inhibitor used to treat adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose disease has progressed on or after platinum-based chemotherapy.

This drug may have the following side effects:
  • shortness of breath,
  • nausea,
  • vomiting,
  • diarrhea,
  • fever,
  • hives, 
  • difficulty breathing, 
  • swelling of your face, lips, tongue, or throat, 
  • fatigue,
  • high blood pressure (hypertension),
  • acute kidney injury, 
  • fluid in the chest, 
  • fast or irregular heartbeats, 
  • swelling in the legs, and
  • rapid heartbeat
The following drugs are related to Exkivity, either as a replacement or used together:
  • Abraxane (albumin-bound paclitaxel for injectable suspension)
  • Krazati (adagrasib tablets)
  • Gilotrif (afatinib tablets, for oral use)
  • Alimta (pemetrexed)
  • Alunbrig (brigatinib tablets)
  • Rybrevant (amivantamab-vmjw for injection)
  • Tecentriq (atezolizumab injection)
  • Avastin (bevacizumab)
  • Mvasi (bevacizumab-awwb solution for intravenous infusion)
  • Zirabev (bevacizumab-bvzr injection)
  • Libtayo (cemiplimab-rwlc injection)
  • Zykadia (ceritinib hard-gelatin capsules)
  • Xalkori (crizotinib)
  • Cyramza (ramucirumab solution for intravenous infusion)
  • Tafinlar (dabrafenib capsules)
  • Imfinzi (durvalumab injection)
  • Rozlytrek (entrectinib capsules)
  • Tarceva (erlotinib)
  • Gavreto (pralsetinib capsules)
  • Iressa (gefitinib)
  • Gemzar (gemcitabine hcl)
  • Keytruda (pembrolizumab for injection)
  • Vitrakvi (larotrectinib capsules)
  • Lorbrena (lorlatinib tablets)
  • Opdivo (nivolumab injection)
  • Tagrisso (osimertinib tablets)
  • Photofrin (porfimer sodium)
  • Retevmo (selpercatinib capsules)
  • Sutent (sunitinib malate)