Drug details

Euflexxa (sodium hyaluronate intra-articular injection, 1%)

type of Rheumatologics, Other, Sodium hyaluronate

Euflexxa (1% sodium hyaluronate) is a cartilaginous defect repair agent indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics (e.g., acetaminophen).

This drug may have the following side effects:

• nausea,
• headache,
• runny or stuffy nose,
• numbness and tingling,
• joint pain,
• injection site pain,
• back pain,
• infection,
• fatigue,
• itching.
• pain in extremities,
• musculoskeletal pain,
• bronchitis,
• arthritis,
• increased blood pressure,
• joint swelling,
• fluid accumulation around the joints,
• tendonitis,
• skin redness, and

The following drugs are related to Euflexxa, either as a replacement or used together:

• Celebrex (celecoxib)
• Gel-One (cross-linked hyaluronate viscoelastic hydrogel)
• Daypro (oxaprozin caplets)
• Daypro Alta (oxaprozin)
• Dolobid (diflunisal)
• Feldene (piroxicam)
• Hymovis (high molecular weight viscoelastic hyaluronan)
• Orthovisc (hyaluronan)
• Orudis (ketoprofen)
• Mobic (meloxicam)
• Relafen (nabumetone)
• Ultram (tramadol hcl)
• Ultram ER (tramadol hcl extended-release)