Drug details

Vagifem (estradiol vaginal tablets)

type of Vaginal Preparations, Other, Estrogen Derivatives

Vagifem (estradiol vaginal) is a female hormone (estrogen) used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching).

This drug may have the following side effects:
  • nausea,
  • vomiting,
  • diarrhea,
  • confusion,
  • yellowing of the skin or eyes (jaundice),
  • dizziness,
  • pain spreading to your jaw or shoulder,
  • constipation,
  • fainting,
  • sweating,
  • chest pain or pressure,
  • muscle weakness,
  • sudden numbness or weakness (especially on one side of the body),
  • slurred speech,
  • problems with vision or balance,
  • coughing up blood,
  • increased thirst or urination,
  • memory problems,
  • sudden vision loss,
  • muscle pain,
  • unusual vaginal bleeding,
  • sudden severe headache,
  • stabbing chest pain,
  • pain or warmth in one or both legs,
  • unusual behavior,
  • lump in your breast,
  • pelvic pain,
  • swelling or tenderness in your stomach,
  • bone pain, and
  • lack of energy
  • fever with nausea,
  • feeling short of breath,
  • sunburn like skin rash,
The following drugs are related to Vagifem, either as a replacement or used together:
  • Premarin (conjugated estrogens)
  • Premarin Injection (conjugated estrogens for injection)
  • Premarin Vaginal Cream (conjugated estrogens vaginal cream)
  • Estratest (esterified estrogens and methyltestosterone)
  • Estrace (estradiol)
  • Estrace Vaginal Cream (estradiol vaginal cream)
  • Estraderm (estradiol transdermal)
  • Mimvey (estradiol and norethindrone acetate tablets)
  • EstroGel (estradiol gel)
  • Estrasorb (estradiol topical emulsion)
  • Estring (estradiol vaginal ring)
  • Estrostep 21 (norethindrone acetate-ethinyl estradiol-ferrous fumarate)
  • Estrostep Fe (norethindrone acetate-ethinyl estradiol-ferrous fumarate)
  • Femhrt (norethindrone acetate, ethinyl estradiol)
  • Veozah (fezolinetan tablets)
  • Fyavolv (norethindrone acetate and ethinyl estradiol tablets)
  • Intrarosa Vaginal Inserts (prasterone)
  • Jinteli (norethindrone acetate and ethinyl estradiol tablets, usp)
  • Kisqali (ribociclib tablets)
  • Kisqali FeMara Co-Pack (ribociclib and letrozole tablets)
  • Lupaneta Pack (leuprolide acetate for depot suspension; norethindrone acetate tablets)
  • Osphena (ospemifene tablets)