Drug details

Estrace Vaginal Cream (estradiol vaginal cream)

type of Vaginal Preparations, Other, Estrogen Derivatives

Estrace (estradiol) vaginal cream is a preparation of estrogen, a female hormone, for topical application to the vaginal area used to treat certain symptoms of menopause such as dryness, burning, and itching of the vaginal area and urgency or irritation with urination.

This drug may have the following side effects:
  • nausea,
  • vomiting,
  • stomach pain,
  • headache,
  • mood changes,
  • bloating,
  • vaginal itching or discharge,
  • weight changes,
  • breast tenderness,
  • breast lumps,
  • spotting or breakthrough bleeding,
  • dark areas of the skin on the face (melasma), or
  • problems wearing contact lenses
The following drugs are related to Estrace Vaginal Cream, either as a replacement or used together:
  • Amabelz (estradiol and norethindrone acetate tablets)
  • Duavee (conjugated estrogens and bazedoxifene tablets)
  • Covaryx (estrogens, esterified and methyltestosterone tablets)
  • Divigel (estradiol gel)
  • Evamist (estradiol)
  • EstroGel (estradiol gel)
  • Estrasorb (estradiol topical emulsion)
  • Vagifem (estradiol vaginal tablets)
  • Osphena (ospemifene tablets)