Drug details

Estrace (estradiol)

type of Vaginal Preparations, Other, Estrogen Derivatives

Estrace (estradiol) is a female hormone (estrogen) used to treat certain symptoms of menopause such as dryness, burning, and itching of the vaginal area and urgency or irritation with urination. Estrace is available in generic form.

This drug may have the following side effects:
  • nausea,
  • headache,
  • vomiting,
  • weight changes,
  • stomach upset,
  • stomach cramps,
  • vaginal itching or discharge,
  • bloating,
  • freckles or darkening of facial skin,
  • loss of scalp hair,
  • breast tenderness/pain/swelling,
  • changes in your menstrual periods, or
  • break-through bleeding.
The following drugs are related to Estrace, either as a replacement or used together:
  • Amabelz (estradiol and norethindrone acetate tablets)
  • Atelvia (risedronate sodium delayed-release tablets)
  • Premarin (conjugated estrogens)
  • Duavee (conjugated estrogens and bazedoxifene tablets)
  • Premarin Injection (conjugated estrogens for injection)
  • Prempro, Premphase (conjugated estrogens, medroxyprogesterone acetate)
  • Covaryx (estrogens, esterified and methyltestosterone tablets)
  • Prolia (denosumab injection)
  • Divigel (estradiol gel)
  • Vagifem (estradiol vaginal tablets)
  • Menest (estrogens)
  • Ogen (estropipate)
  • Evista (raloxifene)
  • Pluvicto (lutetium lu 177 vipivotide tetraxetan)
  • Provera (medroxyprogesterone acetate tablets)
  • Osphena (ospemifene tablets)
  • Prometrium (progesterone)
The following supplements are related to Estrace, and may be used together with the drug:
  • Zinc (s.)
  • Magnesium (s.)
  • Calcium (s.)
  • Fish Oil (s.)
  • Vitamin D (s.)
  • Copper (s.)
  • Beta-Carotene (s.)
  • Dhea (s.)
  • St. John's Wort (s.)
  • Propionyl-L-Carnitine (s.)
  • Kava (s.)
  • Soy (s.)
  • Strontium (s.)
  • Black Cohosh (s.)
  • Fluoride (s.)
  • Ipriflavone (s.)
  • Manganese (s.)