Drug details

Entresto (sacubitril and valsartan film-coated tablets for oral administration)

type of Angiotensin Receptor Blockers (ARBs), Angiotensin Receptor-Neprilysin Inhibitors (ARNi), Neprilysin Inhibitors

Entresto (sacubitril and valsartan) is a combination of a neprilysin inhibitor and an angiotensin II receptor blocker indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction.

The drug is often used to treat Heart failure .

This drug may have the following side effects:

• dizziness,
• cough,
• low blood pressure
• swelling, and
• high blood potassium (hyperkalemia),

The following drugs are related to Entresto, either as a replacement or used together:

• Zaroxolyn (metolazone tablets)