Drug details

Synjardy (empagliflozin and metformin hydrochloride tablets)

type of Antidiabetics, SGLT2 Inhibitors, Antidiabetics, Biguanides

Synjardy (empagliflozin and metformin hydrochloride) is a combination of a sodium-glucose co-transporter 2 (SGLT2) inhibitor and a biguanide, indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are not adequately controlled on a regimen containing empagliflozin or metformin, or in patients already being treated with both empagliflozin and metformin. Synjardy is not for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • vomiting,
  • diarrhea,
  • fever,
  • confusion,
  • rapid breathing,
  • dizziness,
  • blurred vision,
  • dry mouth,
  • little or no urination,
  • increased urination,
  • fruity breath odor,
  • flushing,
  • drowsiness,
  • shaking,
  • hunger,
  • fainting
  • fast heartbeat,
  • feeling unwell,
  • lightheadedness, and
  • pink or bloody urine,
  • heavy sweating,
  • thirst,
  • sudden sweating,
  • unusual discharge from the penis,
  • burning or painful urination,
  • frequent or urgent urination,
  • unusual vaginal discharge, burning, itching, or odor,
  • redness, itching, swelling of the penis,
  • pain, redness, or swelling in or around the genital or anal area,
  • tingling hands or feet,
The following drugs are related to Synjardy, either as a replacement or used together:
  • Precose (acarbose)
  • Lipitor (atorvastatin calcium)
  • Invokana (canagliflozin tablets)
  • Cozaar (losartan potassium)
  • Farxiga (dapagliflozin film-coated tablets)
  • Zegalogue (dasiglucagon injection)
  • Trijardy XR (empagliflozin, linagliptin, and metformin hydrochloride extended-release tablets)
  • Glucotrol (glipizide)
  • Glucotrol XL (glipizide extended release)
  • NovoLog (insulin aspart [rdna origin] inj)
  • NovoLog Mix 70/30 (insulin aspart protamine and insulin aspart (rdna origin))
  • Semglee (insulin glargine injection)
  • Lyumjev (insulin lispro-aabc injection)
  • Janumet (sitagliptin metformin hcl)
  • Janumet XR (sitagliptin and metformin hcl)
  • NovoLog Mix 50/50 (50% insulin aspart protamine suspension and 50% insulin aspart injection)