Drug details

Oriahnn (elagolix, estradiol, and norethindrone acetate capsules; elagolix capsules)

type of Gonadotropin Releasing Hormone Antagonists, Estrogens/Progestins

Oriahnn (elagolix, estradiol, and norethindrone acetate capsules; elagolix capsules) is a combination of a gonadotropin-releasing hormone (GnRH) receptor antagonist, an estrogen, and a progestin used to manage heavy menstrual bleeding associated with uterine leiomyomas (fibroids) in premenopausal women. Use of Oriahnn should be limited to 24 months due to the risk of continued bone loss, which may not be reversible.

This drug may have the following side effects:

• headache,
• fatigue, and
• hot flushes,
• bleeding between periods

The following drugs are related to Oriahnn, either as a replacement or used together:

• Mirena (levonorgestrel-releasing intrauterine system)
• Liletta (levonorgestrel-releasing intrauterine system)
• Lysteda (tranexamic acid tablets)
• Myfembree (relugolix, estradiol, and norethindrone acetate tablets)