Drug details

Orilissa (elagolix tablets)

type of Gonadotropin Releasing Hormone Antagonists

Orilissa (elagolix) is a gonadotropin-releasing hormone (GnRH) receptor antagonist indicated for the management of moderate to severe pain associated with endometriosis.

The drug is often used to treat Endometriosis .

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • nausea,
  • yellowing of the skin or eyes (jaundice)
  • vomiting,
  • easy bruising,
  • tiredness,
  • stomach pain (upper right side),
  • dark urine, and
  • anxiety,
  • mood or behavior changes,
  • depression,
  • thoughts about suicide,
The following drugs are related to Orilissa, either as a replacement or used together:
  • NuvaRing (etonogestrel, ethinyl estradiol vaginal ring)
  • Kyleena (levonorgestrel)
  • Seasonique (levonorgestrel, ethinyl estradiol)
  • Mirena (levonorgestrel-releasing intrauterine system)
  • Liletta (levonorgestrel-releasing intrauterine system)
  • Sprintec (norgestimate and ethinyl estradiol tablets)
  • Tri-Sprintec (norgestimate and ethinyl estradiol tablets-triphasic regimen)