Drug details

Safyral (drospirenone/ethinyl estradiol/levomefolate calcium tablets and levomefolate)

type of Contraceptives, Oral, Estrogens/Progestins

Safyral (drospirenone/ethinyl estradiol/levomefolate calcium) is a combination of female hormones and vitamin B used as contraception to prevent pregnancy.

This drug may have the following side effects:
  • vomiting,
  • headache,
  • bloating,
  • increased hair growth,
  • problems with contact lenses, or
  • nipple discharge,
  • freckles or darkening of facial skin,
  • loss of scalp hair,
  • weight changes,
  • vaginal itching or discharge.
  • stomach cramps,
  • breast tenderness or swelling,
  • swelling of the ankles/feet (fluid retention),
  • nausea (especially when you first start taking Safyral),
The following drugs are related to Safyral, either as a replacement or used together:
  • Annovera (segesterone acetate and ethinyl estradiol vaginal system)
  • Yasmin (drospirenone and ethinyl estradiol)
  • Yaz (drospirenone and ethinyl estradiol)
  • NuvaRing (etonogestrel, ethinyl estradiol vaginal ring)
  • Orsythia (levonorgestrel and ethinyl estradiol tablets)
  • Provera (medroxyprogesterone acetate tablets)
  • Ortho Evra (norelgestromin, ethinyl estradiol transdermal)
  • Wymzya Fe (norethindrone and ethinyl estradiol tablets (chewable) and ferrous fumarate] tablets)
  • Ortho Tri-Cyclen / Ortho-Cyclen (norgestimate and ethinyl estradiol)