Drug details

Nikki (drospirenone and ethinyl estradiol tablets)

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Nikki (drospirenone and ethinyl estradiol tablets) is a birth control pill that contains two female hormones, a synthetic estrogen and a progestin, used help to lower the chances of becoming pregnant when taken as directed. They do not protect against HIV infection (AIDS) and other sexually transmitted diseases. Nikki is available as a generic.

The drug is often used to treat HIV .

This drug may have the following side effects:
  • itching,
  • dark urine,
  • rash,
  • confusion,
  • fainting,
  • muscle weakness,
  • mood changes,
  • slurred speech,
  • elevated blood pressure,
  • depression,
  • unusual sweating,
  • weakness on one side of the body,
  • severe dizziness, and
  • trouble breathing
  • vision changes,
  • coughing up blood,
  • sudden dizziness,
  • yellowing of the eyes or skin (jaundice),
  • slow or irregular heartbeat,
  • lack of coordination,
  • sudden shortness of breath,
  • lumps in the breast,
  • unusual changes in vaginal bleeding (continuous spotting, sudden heavy bleeding, missed periods),
  • unusual headaches,
  • sudden, very severe headaches,
  • partial or complete blindness,
  • severe abdominal pain,
  • pain, swelling, or warmth in the groin or calf,
  • swelling of the face, tongue, or throat,
  • suicidal thoughts,
  • chest pain extending to your jaw or left arm,
  • tingling, weakness, or numbness in the arms or legs,
  • worsening migraines,
The following drugs are related to Nikki, either as a replacement or used together:
  • Depo-Provera (medroxyprogesterone)
  • Yasmin (drospirenone and ethinyl estradiol)
  • Yaz (drospirenone and ethinyl estradiol)
  • Implanon (etonogestrel implant)
  • Nexplanon (etonogestrel implant)
  • ParaGard (intrauterine copper contraceptive)
  • Mirena (levonorgestrel-releasing intrauterine system)
  • Skyla (levonorgestrel-releasing intrauterine system)
  • Liletta (levonorgestrel-releasing intrauterine system)
  • Ortho-Novum (norethindrone and ethinyl estradiol)
  • Ortho Tri-Cyclen / Ortho-Cyclen (norgestimate and ethinyl estradiol)
  • TriNessa (norgestimate and ethinyl estradiol tablets)
  • Previfem (norgestimate and ethinyl estradiol tablets)
  • Ortho Tri-Cyclen Lo (norgestimate, ethinyl estradiol)