Drug details

Zonalon (doxepin)

type of Topical Skin Products

Zonalon (doxepin hydrochloride) Cream 5% is a tricyclic antidepressant used to relieve troublesome itching from certain skin conditions (e.g. atopic dermatitis eczema neurodermatitis). Zonalon should be used only for a short time (no more than 8 days).

This drug may have the following side effects:
  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • confusion,
  • severe drowsiness,
  • painful or difficult urination,
  • blurred vision, and
  • severe dry mouth,
  • new or worsening skin symptoms
The following drugs are related to Zonalon, either as a replacement or used together:
  • Recedo (medical-grade topical silicone, topical gel)
  • Opzelura (ruxolitinib cream)