Drug details

Jemperli (dostarlimab-gxly injection)

type of Monoclonal Antibodies, PD-1PD-L1 Inhibitors, Antineoplastics Monoclonal Antibody

Jemperli (dostarlimab-gxly) is a programmed death receptor-1 (PD-1)–blocking antibody used to treat adult patients with mismatch repair deficient (dMMR) recurrent or advanced endometrial cancer, as determined by an FDA-approved test, that has progressed on or following prior treatment with a platinum-containing regimen.

This drug may have the following side effects:
  • shortness of breath,
  • chest pain,
  • nausea,
  • sweating,
  • lightheadedness,
  • dizziness,
  • vomiting,
  • diarrhea,
  • weakness,
  • sore throat,
  • itching,
  • constipation,
  • loss of appetite,
  • fever,
  • chills,
  • pale skin,
  • tiredness,
  • hives, 
  • difficulty breathing, 
  • swelling of your face, lips, tongue, or throat, 
  • easy bruising, 
  • severe stomach pain, 
  • bloody or tarry stools, 
  • confusion, 
  • vision problems, 
  • dark urine, 
  • hair loss,
  • mood or behavior changes,
  • increased urination, 
  • unusual bleeding, 
  • hallucinations, 
  • yellowing of the skin or eyes (jaundice),
  • eye pain or redness, 
  • skin pain, 
  • little or no urination, 
  • cold hands and feet, 
  • burning eyes, 
  • red or purple skin rash with blistering and peeling, 
  • new or worsening cough, 
  • irregular heartbeats, 
  • seizure, 
  • swelling in your ankles, 
  • blood in your urine, 
  • right-sided upper stomach pain, 
  • frequent or unusual headaches, 
  • hoarse or deepened voice, 
  • increased hunger or thirst, 
  • feeling cold, and
  • weight gain or loss
The following drugs are related to Jemperli, either as a replacement or used together:
  • Keytruda (pembrolizumab for injection)
  • Lenvima (lenvatinib capsules)
  • Megestrol Acetate Tablets (megestrol acetate tablets)