Drug details

Totect (dexrazoxane for injection, intravenous infusion only)

type of Cardioprotectant Agents

Totect (dexrazoxane for injection) protects the heart and other tissues from harmful side effects caused by certain cancer medications and is used to reduce serious tissue injury if doxorubicin or a similar cancer chemotherapy medication has leaked out of the vein into the surrounding tissue. Totect can help prevent the need for surgery to repair the tissue damage.

This drug may have the following side effects:

• sore throat
• dizziness
• swelling in your hands or feet
• hair loss
• tired feeling, or
• trouble swallowing
• injection site reactions (pain, swelling, or redness)

The following drugs are related to Totect, either as a replacement or used together:

• Arimidex (anastrozole)
• Aredia (pamidronate disodium)
• Aromasin (exemestane)
• Xeloda (capecitabine)
• Capecitabine (Xeloda) Tablets (capecitabine tablets)
• Cytoxan (cyclophosphamide)
• Docefrez (docetaxel)
• Ellence (epirubicin hydrochloride)
• Faslodex (fulvestrant)
• Femara (letrozole)
• Sancuso (granisetron transdermal system)
• Herceptin (trastuzumab)
• Nolvadex (tamoxifen citrate)
• Soltamox (tamoxifen citrate)